809094 Biomarker Identification in Fracture Healing (experiment #3808 miRNA)

ABSTRACT: The specific genes that distinguish normal fracture healing from abnormal healing or nonunion in humans are unknown. This study explored global RNA expression in remnant bone fragments from acutely injured patients undergoing open primary fracture repair surgery. These data will be compared to blood samples collected from acutely injured subjects, chronic nonunion subjects, and a panel of healthy volunteers. We used microarrays to do a global comparison across bone fragments collected from different patients, and different bones. We also evaluated the role of remnant bone preparation which was either immediate freezing in liquid nitrogen or heat stabilized with the Denator Stabilizer(TM) system.

ORGANISM(S): synthetic construct Homo sapiens

PROVIDER: GSE93397 | GEO | 2017/01/11

SECONDARY ACCESSION(S): PRJNA360867

REPOSITORIES: GEO