Other

Dataset Information

0

Eomes related gene regulation in Definitive Endoderm (NG Capture-C)


ABSTRACT: Precisely co-ordinated activation of lineage specific transcription factors direct cell fate decisions during mouse early development. The T-box transcription factor Eomes is dynamically expressed during mouse gastrulation and is a key regulator of the anterior visceral endoderm (AVE), cardiac mesoderm and definitive endoderm (DE) lineages. The cis-acting regulatory elements that direct spatiotemporally restricted Eomes expression domains have yet to be elucidated. To understand transcriptional regulation of Eomes in Definitive Endoderm open chromatin data was generated by ATAC-seq and histone modifications identified by ChIP-seq. Interactions at the Eomes locus and the loci of two related transcription factors Foxa2 and Lhx1, was also determined by NG Capture-C.

ORGANISM(S): Mus musculus

PROVIDER: GSE94051 | GEO | 2017/01/30

SECONDARY ACCESSION(S): PRJNA369203

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2017-01-30 | GSE94048 | GEO
2017-01-30 | GSE94249 | GEO
| PRJNA369195 | ENA
2015-10-19 | GSE70956 | GEO
2019-12-02 | GSE128466 | GEO
2017-04-10 | GSE85585 | GEO
2011-01-25 | E-GEOD-26097 | biostudies-arrayexpress
2023-05-19 | GSE198780 | GEO
2018-11-26 | GSE122888 | GEO
2011-01-25 | GSE26097 | GEO