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Chip-chip from THP1 and HUVEC cells with ROR-alpha

ABSTRACT: ROR-alpha is a nuclear receptor, activity of which can be modulated by natural or synthetic ligands including cholesterol. Due to its possible involvement in, and potential therapeutic target for atherosclerosis, we aimed to identify ROR-alpha target genes in monocyte and endothelial cell lines, THP1 and HUVEC, respectively. ChIP-on-chip analysis of ROR-alpha demonstrated that ROR-alpha may target more than 3000 genes in monocytic and endothelial cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE94079 | GEO | 2017/02/28

SECONDARY ACCESSION(S): PRJNA368744

REPOSITORIES: GEO

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