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Genome-wide CRISPR knockout to screen for essential targets for HCC cell growth

ABSTRACT: We performed genome-wide functional knockout screens using GECKOv2 library to identify essential growth targets in two hepatocellular carcinoma (HCC) cell lines, HCCLM3 and SNU449. We compared the gRNA present at the end of 10 passages (End Point) vs. that at Time zero in these two cell lines separately then overlap for common targets.

ORGANISM(S): Homo sapiens

PROVIDER: GSE94509 | GEO | 2019/08/20

REPOSITORIES: GEO

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