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RNASeq of juvenile keratinocytes, melanocytes, fibroblasts and whole skin

ABSTRACT: We used whole transcriptome sequencing (RNA-Seq) to assess differential gene expression of normal human melanocytes with respect to keratinocytes, fibroblasts and whole skin. We have identified a number of genes and pathways, which are characteristic or unique for MC compared to KC and FB. We also demonstrated the extent of the difference between genes detectable in MC culture and the whole skin. The present results reveal melanocytes as highly proliferative cells with stem cell-like properties.

ORGANISM(S): Homo sapiens

PROVIDER: GSE94655 | GEO | 2017/02/09

SECONDARY ACCESSION(S): PRJNA371742

REPOSITORIES: GEO

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Effect of enhanced melanin synthesis on the production of extracellular vesicles in melanocytes and communication with keratinocytes

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