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Regulatory elements governing neurogenesis and proliferation in developing human neocortex

ABSTRACT: Non-coding regions compose most of the human genome, yet their functionality is poorly defined. In the developing human neocortex, non-coding regulatory elements tightly regulate expression to direct neural progenitor proliferation and neurogenesis. Here, we define thousands of non-coding elements involved in human neurogenesis by contrasting chromatin accessibility via ATAC-seq from the germinal zone and cortical plate.

ORGANISM(S): Homo sapiens

PROVIDER: GSE95023 | GEO | 2018/01/11

SECONDARY ACCESSION(S): PRJNA375750

REPOSITORIES: GEO

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