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Genome-wide maps of chromatin state and chromatin accessibility in CD8 T cell subsets

ABSTRACT: To understand epigenetic mechanisms underlying CD8 T cell differentiation, we performed ChIP-seq of 4 histone modifications (H3K4me1, H3K4me3, H3K27ac, H3K27me3) and ATAC-seq to probe chromatin states and accessibility. We identified subset-specific regulatory elements (enhancers and promoters) from chromatin states and predicted key transcription factors from accessible regulatory regions using ATAC-seq.

ORGANISM(S): Mus musculus

PROVIDER: GSE95237 | GEO | 2017/03/13

SECONDARY ACCESSION(S): PRJNA376705

REPOSITORIES: GEO

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