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Assessing the impact of the R252W Charcot-Marie-Tooth disease mutation in MORC2 on HUSH-mediated repression

ABSTRACT: HeLa cells lacking MORC2 generated through CRISPR/Cas9-mediated gene disruption were reconstituted with either wild-type or R252W mutant MORC2, and re-repression of HUSH target genes assessed by RNA-seq

ORGANISM(S): Homo sapiens

PROVIDER: GSE95455 | GEO | 2017/05/29

SECONDARY ACCESSION(S): PRJNA377249

REPOSITORIES: GEO

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Project description:This SuperSeries is composed of the SubSeries listed below.

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