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A genome-wide CRISPR/Cas9 screen to identify genes required for transgene silencing in human cells

ABSTRACT: A population of KBM7 cells harboring epigenetically-repressed GFPdim transgenes was mutagenized using a genome-wide CRISPR sgRNA library, and GFPbright cells containing relevant gene disruption events isolated by two rounds of FACS.

ORGANISM(S): Homo sapiens

PROVIDER: GSE95458 | GEO | 2017/05/29

SECONDARY ACCESSION(S): PRJNA377246

REPOSITORIES: GEO

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