Transcriptomics

Dataset Information

0

Expression data from acd, p53 and double mutant mouse embryos


ABSTRACT: In mouse, the adrenocortical dysplasia (acd) phenotype shows limb and body axis anomalies, as a result of p53-dependent apoptosis, and perinatal lethality. The p53 deficiency partially rescues anomalies, but not perinatal lethality, implicating the involvement of p53-independent mechanisms in the acd phenotype. Differentially expressed genes in acd mutant and double mutant embryos were identified. p53-dependent and –independent pathways contributing to acd phenotype were characterized. We used microarrays to analyze gene expression profiles of acd and double mutant embryos and to identify p53 dependent and –independent mechanisms underlying acd phenotype.

ORGANISM(S): Mus musculus

PROVIDER: GSE95806 | GEO | 2018/09/07

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2009-04-07 | E-TABM-680 | biostudies-arrayexpress
| PRJNA378483 | ENA
2012-06-01 | E-MTAB-1001 | biostudies-arrayexpress
2019-09-20 | GSE132133 | GEO
2017-02-09 | GSE83465 | GEO
2007-07-01 | GSE8027 | GEO
2024-01-26 | PXD028462 | Pride
2022-03-11 | GSE155240 | GEO
2011-01-21 | E-GEOD-26723 | biostudies-arrayexpress
2019-10-31 | E-MTAB-7322 | biostudies-arrayexpress