Transcriptomics

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The Quantitative Analysis of Transcriptomes Derived From Ezh2- or Ezh1/2-Deleted Leukemia Stem Cells of Murine Acute Myloid Leukemia


ABSTRACT: We report dual genetic delstion of Ezh1/2 in murine AML model induced cell cyle progression of quiescent LSCs and cell differentiation of LSCs. To investigate the underlying mechanism by which Ezh1/2 regulate quiescent LSCs and maintein the stemness of LSCs, we performed RNA sequencing of L-GMPs derived from Ezh2- and Ezh1/2-deleted AML mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE96061 | GEO | 2017/03/11

SECONDARY ACCESSION(S): PRJNA378715

REPOSITORIES: GEO

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