Transcriptomics

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Canakinumab treatment in hyperimmunoglobulinemia D with periodic fever syndrome


ABSTRACT: Objective. To evaluate the efficacy and safety of canakinumab treatment in active hyperimmunoglobulinemia D with periodic fever syndrome (HIDS). Methods. This is a 3-part open-label study with a 6-month treatment period (P1; 300 mg or 4 mg/kg q6w) a 6-month withdrawal period (P2) and a 24-month treatment period (P3). The primary endpoint was reduction in frequency of flares during treatment period compared with the historical period (HP; period in which patients did not receive drugs other than NSAIDs and/or steroids).

ORGANISM(S): Homo sapiens

PROVIDER: GSE97075 | GEO | 2018/09/17

REPOSITORIES: GEO

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