Microarray expression profile of long noncoding RNAs in germinal center-like diffuse large B-cell lymphoma cell lines.
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ABSTRACT: The contributions of long noncoding RNAs (lncRNAs) to the development of germinal center (GCB)-like diffuse large B-cell lymphoma (DLBCL) remain largely unknown. The aim of this study was to investigate the expression profile of lncRNAs in human GCB DLBCL cell lines (OCI-ly1 and OCI-ly19) and normal B lymphocytes by microarray. We demonstrated that 21,539 lncRNAs were expressed in all samples analyzed, of which 1,648 lncRNAs were upregulated and 2,671 lncRNAs were downregulated in GCB DLBCL cell lines (OCI-ly1 and OCI-ly19) (≥2.0-fold, P<0.05).
ORGANISM(S): Homo sapiens
PROVIDER: GSE97336 | GEO | 2019/01/01
REPOSITORIES: GEO
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