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Transcriptomic analysis of conditional THAP1 knockout mice brains using microarray

ABSTRACT: Loss of function mutations in the transcription factor THAP1 cause DYT6 dystonia, a childhood-onset motor disorder. DYT6 subjects display abnormalities in the white matter regions of the brain. Here, we generated conditional THAP1 knockout mice and analyzed the gene expression profiles from motor regions of mice brains to identify a role for THAP1 in the control of myelination

ORGANISM(S): Mus musculus

PROVIDER: GSE97372 | GEO | 2017/07/10

SECONDARY ACCESSION(S): PRJNA381540

REPOSITORIES: GEO

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