Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Identification and development of DNA methylation biomarkers for oral/oropharyngeal cancers prevalent in the North-Eastern states of India

ABSTRACT: Whole-genome DNA methylation profiling of oral cancer in patients from North-Eastern states of India. The Illumina Infinium 450k Human DNA methylation BeadChip was used to screen the entire DNA methylation profiles across approximately 485,577 CpGs in matched oral cancer samples. Samples included 12 paired samples (12 cancer and 12 normal).

ORGANISM(S): Homo sapiens

PROVIDER: GSE97784 | GEO | 2019/04/09

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Identification and development of DNA methylation biomarkers for Stomach cancers prevalent in Mizoram, India

Project description:Whole genome DNA methylation profiling of stomach cancer in patients from Mizoram, India. The Illumina Infinium 450k Human DNA methylation Beadchip was used to screen the entire DNA methylation profiles across approximately 485,577 CpGs in matched stomach cancer samples. Samples included 12 paired samples (12 cancer and 12 normal).

2021-07-01 | GSE164988 | GEO

Whole Genome DNA Methylation and Gene Expression Profiling of Oropharyngeal Cancer Patients in North-Eastern India

Project description:Methylation of CpG Islands within promoter regions of genes has been associated with gene silencing, suggesting loss of tumor suppressor function and tumorigenesis. The northeastern states of India are leaders in the country for cancers of several sites. Almost no reports are available of any DNA methylation biomarker for oropharyngeal cancers of the northeastern states. The present study aimed to identify targets of CpG hypermethylation and hypomethylation in oropharyngeal cancer prevalent in northeast India. Using Illumina Infinium Human Methylation 450K microarray platform a genome wide screening has been done for differentially methylated genes, including genes not previously implicated in carcinogenesis. Differential gene expression correlated to their methylation status was elaborated using transcriptome profiling. The new genes identified may be used to develop promising panels of DNA Methylation biomarkers for oropharyngeal screening and detection at a very early stage.

2020-09-25 | GSE136704 | GEO

Ethnic specific genetic variation alters smoking associated DNA methylation at HIV co-receptor GPR15

Project description:Genome wide DNA methylation profiling of smokers and non-smokers in PBMC samples. The Illumina Infinium 450k Human DNA methylation Beadchip v1.1 was used to obtain DNA methylation profiles across 485,577 CpGs in PBMC samples. Samples included 24 smokers and 28 non-smokers.

2017-02-13 | GSE59550 | GEO

Epigenome analysis of smoking in peripheral blood mononuclear cells (PBMC) samples

2014-02-27 | GSE53045 | GEO

DNA methylation analysis in malignant melanoma clinical samples [450K array]

Project description:Comprehensive DNA methylation analysis in malignant melanoma clinical samples. Infinium HumanMethylation450 BeadChip was used to obtain DNA methylation profiles across 485,577 CpG sites. Samples included 54 malignant melanoma cases and primary melanocyte culture.

2020-10-22 | GSE140169 | GEO

DNA methylation analysis in oropharyngeal cancer [450K array]

Project description:DNA methylation analysis in oropharyngeal squamous carcinoma (OPSCC) samples and oropharyngeal non-cancerous mucosa samples. Infinium HumanMethylation450 BeadChip was used to obtain DNA methylation profiles across 485,577 CpG sites. Total samples included 89 OPSCC samples and 5 non-cancerous mucosa samples.

2020-01-20 | GSE124464 | GEO

Epigenome analysis of alcohol consumption in whole blood (WB) samples

Project description:Genome wide DNA methylation profiling of drinkers and non-drinkers in WB samples. The Illumina Infinium EPIC Human DNA methylation Beadchip was used to obtain DNA methylation profiles across 485,577 CpGs in WB samples that oevrlapped with CpGs from Illumina Infinium450k Human DNA methylation Beadchip. Samples included 47 drinkers (cases) and 47 non-drinkers (controls).

2018-04-01 | GSE110043 | GEO

OSCC CGH SriLanka vs India

Project description:In Asia, oral cancer (OC) and oral submucous fibrosis (OSF) constitute major health problems linked to use of betel quid. This work performed CGH genome-wide analysis of OC (12 from India, 12 from Sri Lanka) and OSF (6 from India) cases with normal controls.

2011-11-30 | E-MTAB-819 | biostudies-arrayexpress

Epigenome analysis of cirrhosis and dysplastic liver samples

Project description:Genome-wide DNA methylation profiling of cirrhosis and dysplastic liver samples. The Illumina Infinium 450k Human DNA methylation BeadChip was used to obtain DNA methylation profiles across approximately 485,577 CpGs sites. Samples included 130 cirrhosis and 8 exhibiting dysplasia. The manuscript includes an integrative analysis of these samples along with samples from normal liver and HCC already deposited under GSE63898.

2021-06-02 | GSE157973 | GEO

A low DNA methylation epigenotype in squamous cell lung cancer and its association with idiopathic pulmonary fibrosis and poorer prognosis

Project description:Comprehensive DNA methylation analysis in clinical samples of lung squamous cell carcinoma with or without tidiopathic pulmonary fibrosis. Infinium HumanMethylation450 BeadChip was used to obtain DNA methylation profiles across 485,577 CpG sites. Samples included 20 lung squamous cell carcinoma with or without tidiopathic pulmonary fibrosis and 13 surrounding lung samples.

2019-10-26 | GSE121849 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data