Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Monocular Visual Deprivation in Macaque Monkeys: A Profile in the Gene Expression of the LGN by LCM

ABSTRACT: Laser capture microdissection was used to obtain individual LGN layers for DNA microarray of Rhesus array in macaque monkeys that Monocular Visual Deprivation was generated by either opaque dark contact lens or tarsoraphoplasty at birth. Keywords: Lateral Geniculate Nucleus, monocular deprivation, Rhesus array, Laser Capture Microdissection, Gene expression

ORGANISM(S): Macaca mulatta

PROVIDER: GSE9795 | GEO | 2008/12/01

SECONDARY ACCESSION(S): PRJNA103735

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Transcriptional Profile Analysis of the Lateral Geniculate Nucleus in Monocular Deprived Macaque Monkeys

Project description:Laser capture microdissection was used to obtain individual LGN layers for DNA microarray in macaque monkeys that underwent monocular eyelid suture at birth. Keywords: parallel sample

2007-07-20 | GSE2165 | GEO

Transcription profiling of macaque lateral geniculate nucleus in monocular deprived animals

Project description:Laser capture microdissection was used to obtain individual LGN layers for DNA microarray in macaque monkeys that underwent monocular eyelid suture at birth.

2008-06-11 | E-GEOD-2165 | biostudies-arrayexpress

Laser capture microdissected vervet monkey lateral geniculate nucleus hybridized to the Rhesus Macaque Genome Array.

Project description:This report is based on an ongoing study to examine gene expression differences in monkey lateral geniculate nucleus (LGN). For this study, samples from an Old World species, vervet monkey (Cercopithecus aethiops), were cross-hybridized to the Rhesus Macaque Genome Array (Affymetrix). Microarray analysis was performed using laser capture microdissected populations of individual neuronal cell bodies isolated from the LGN compared to heterogeneous samples from whole lamina. We show here that cross-species hybridization of microdissected brain tissue samples from vervet monkeys to the Rhesus array produced reliable and biologically relevant data sets. We present the first list of genes enriched in the large neuronal cell bodies of the LGN. We found that these cell bodies are concentrated with genes involved in metabolic processes and protein synthesis, whereas signaling molecules including chemokines and integrins were expressed at higher levels within heterogeneous samples. Our data set provides support for a contribution of Wnt signaling in adult monkey LGN. Keywords: gene expression profile

2007-11-12 | GSE8859 | GEO

Monocular Visual Deprivation in Macaca Fascicularis: A mRNA Sequencing Profile of LGN Tissues.

Project description:We sutured the left eyelid of one-month-old Macaca Fascicularis. Three months later, their LGN tissues were captured and mRNA sequencing was carried out to study the effect of monocular deprivation on gene expression in Macaca Fascicularis.

2022-01-28 | GSE189488 | GEO

Mouse lung and brain LCM-ATACseq

Project description:In situ transposition followed by laser capture microdissection was applied to lung and brain mouse tissue sections to demonstrate feasibility of LCM-based spatial chromatin accessibility analysis of regions of interest.

2023-12-01 | GSE218216 | GEO

Tumor and stroma from breast by LCM

Project description:Tumor epithelium and surrounding stromal cells were isolated using laser capture microdissection of human breast cancer to examine differences in gene expression based on tissue types from inflammatory and non-inflammatory breast cancer Keywords: LCM

2007-09-30 | GSE5847 | GEO

Mouse spleen LCM-ATACseq (B and T cell zones)

Project description:In situ transposition followed by laser capture microdissection was applied to spleen mouse tissue sections to demonstrate feasibility of LCM-based spatial chromatin accessibility analysis of regions of interest. B220 and CD3e immunostained B and T cell zones were analyzed.

2023-12-01 | GSE237824 | GEO

LCM-Seq analysis of microscopically defined human embryo HSC microenvironment

Project description:This dataset contains RNA-Seq data for cells within spatially defined subdomains of the human embryo dorsal aorta, subdissected from tissue sections using laser capture microdissection. This dataset explores dorsal-ventral polarisation across the dorsal aorta, the site of hematopoietic stem cell emergence.

2020-09-17 | GSE151875 | GEO

Laser Capture Microdissection (LCM) analysis of mycorrhizal rice roots

Project description:Laser Capture Microdissection (LCM) analysis of mycorrhizal rice roots

| PRJNA492135 | ENA

LCM-RNAseq on human pyramidal neurons and parvalbumin interneurons from frontal cortex

Project description:Pyramidal neurons and aggregcan-positive interneurons were collected from healthy control human post-mortem brain tissue (Brodmann Area 9) by laser capture microdissection. RNA was collected from pooled cells from 4 donors, and compared with full stained sections to determine enriched genes expressed in each cell type by RNAseq.

2020-04-23 | GSE149154 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data