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Regional preferences of DNA methylation changes in response to X-ray-irradiation [Agilent-069114 array]

ABSTRACT: In this study we screened for changes of DNA methylation in response to X-irradiation in the lymphoblastoid cell line GM12878 and the primary lung fibroblast cell line IMR90. We employed methylated DNA-Immunoprecipitation in combination with genome wide and region specific DNA microarrays to identify preferences of radiation induced changes of methylation with respect to genomic and epigenomic characteristics.

ORGANISM(S): Homo sapiens

PROVIDER: GSE98305 | GEO | 2018/03/31

REPOSITORIES: GEO

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Regional preferences of DNA methylation changes in response to X-ray-irradiation [Agilent-021850 array]

Project description:In this study we screened for changes of DNA methylation in response to X-irradiation in the lymphoblastoid cell line GM12878 and the primary lung fibroblast cell line IMR90. We employed methylated DNA-Immunoprecipitation in combination with genome wide and region specific DNA microarrays to identify preferences of radiation induced changes of methylation with respect to genomic and epigenomic characteristics.

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