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Cellular Senescence RT2 Profiler PCR Array of replicative senescent and hyperglycemia treated HUVECs

ABSTRACT: Young endothelial cells (CPD >25 and <30; SA-Beta Gal positivity <10%) were exposed to one week of hyperglycemia (25 mmol/L) or sub-cultured until complete growth arrest (CPD > 50). Using real-time PCR, we analyzed the expression of a focused panel of genes involved in cellular senescence.The array includes genes involved in the primary senescence program and known stresses that cause premature senescence.

ORGANISM(S): Homo sapiens

PROVIDER: GSE99013 | GEO | 2017/05/18

SECONDARY ACCESSION(S): PRJNA386998

REPOSITORIES: GEO

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