Global analysis of liver RNA from male and female Wildtype mice vs Ikbkb-deleted in hepatocyte mice fed high cholesterol and saturated fat diet (HCFD)
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
PROVIDER: GSE99031 | GEO | 2017/05/18
SECONDARY ACCESSION(S): PRJNA387032
REPOSITORIES: GEO
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There are 3 disease states: Healthy, Sick, and Dead, where the Dead state is terminal.
The yearly transition probabilities are:
Healthy to Dead: 0.01; Healthy to Sick: 0.2 for Male and 0.1 for Female; Sick to Healthy: 0.1; Sick to Dead: 0.3.
The transition probability now depends on the cohort (Male or Female) and can be expressed as a function of a Boolean covariate Male.
Initial conditions: Healthy = (50 Male, 50 Female), Sick = (0,0) and Dead = (0,0).
Output: Number of men and women in each disease state for years 1-10.
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