Transcriptomics

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RNAseq analysis of wildtype and Nrf2-/- advanced lung tumors


ABSTRACT: Nrf2 plays a critical role in lung cancer. We investigated the gene expression profile in Nrf2 wildtype and knockout tumors. Nrf2 wildtype and knockout mice were injected with 2 or 4 doses of vinyl carbamate (16 mg/kg). Lung tumors were then dissected and pooled from each group to isolate total RNA. RNAseq was then performed to analyze the differential expression profiles between groups.

ORGANISM(S): Mus musculus

PROVIDER: GSE99338 | GEO | 2018/05/16

REPOSITORIES: GEO

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