Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

GNPS_Penicillium allii

ABSTRACT: Penicillium allii raw extract and two major compounds, including Fulvic acid and PI3

INSTRUMENT(S): LCQ Fleet

ORGANISM(S): Penicillium Allii (ncbitaxon:60177)

SUBMITTER: KUNP

PROVIDER: MSV000081502 | GNPS |

REPOSITORIES: GNPS

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

GNPS_Cudrania_Other Instrument

Project description:Cudrania tricuspidata extract and major compounds. Penicillium alli. fungi major compounds and extract

2017-08-16 | MSV000081451 | GNPS

RNA-seq analysis reveals modulation of inflammatory pathways by an enriched-triterpene natural extract in mouse and human macrophage cell lines

Project description:Chronic Inflammation has a key role in the development of insulin resistance and type 2 diabetes. Previously, we demonstrated that OBE100, a natural extract from the leaves of Eucalyptus tereticornis, has anti-inflammatory properties. Three pentacyclic triterpenoids, ursolic acid, oleanolic acid, and ursolic acid lactone are the major compounds present in OBE100. These molecules have shown multiple biological activities. In this study we analyzed how the compounds of OBE100 modify macrophage gene expression using RNA sequencing. Triterpenoids regulate the inflammatory program in activated macrophages inhibiting the expression of many cytokines, chemokines, and inflammatory mediators. However, the OBE100 extract has a more powerful immunomodulatory effect than the triterpene mixture increasing the number of genes regulated, both in mouse and human models. Our study shows that OBE100 is a promising extract for the treatment of diabetes that can break the link between inflammation and insulin resistance.

2023-12-18 | GSE250471 | GEO

Adipogenesis, lipolysis, and extracellular matrix remodeling are early modulated by a triterpene-enriched natural extract in a mouse cell line and primary human adipocytes

Project description:Chronic Inflammation has a key role in the development of insulin resistance and type 2 diabetes. Previously, we demonstrated that OBE100, a natural extract from the leaves of Eucalyptus tereticornis, has anti-inflammatory properties. Three pentacyclic triterpenoids, ursolic acid, oleanolic acid, and ursolic acid lactone are the major compounds present in OBE100. These molecules have shown multiple biological activities. In this study we analyzed how the compounds of OBE100 modify adipocyte gene expression using RNA sequencing. Triterpenoids regulate the inflammatory program in differentiated adipocytes, inhibiting the expression of many cytokines, chemokines, and inflammatory mediators. However, the OBE100 extract has a more powerful immunomodulatory effect than the triterpene mixture increasing the number of genes regulated, both in mouse and human models. Our study shows that OBE100 is a promising extract for the treatment of diabetes that can break the link between inflammation and insulin resistance.

2024-07-31 | GSE272831 | GEO

Effect of deletion of PoxCxrC and overexpression of POX_f08097 in engineering strain Penicillium oxalicum TE4-10 at the transcriptional level

Project description:In order to obtain genetically engineering strain of Penicillium oxalicum with high Raw Starch Digesting Glucoamylase production,we deleted PoxCxrC and overexpressed POX_f08097 in Penicillium oxalicum TE4-10 ,and we want to investigating the function of deletion of PoxCxrC and overexpression of POX_f08097 at transcriptional level.

2022-12-28 | GSE210161 | GEO

Modulation of gene expression induced by supercritical fluid rosemary extract in colon cancer cells

2014-04-04 | GSE56496 | GEO

Comprehensive genomic, phenotypic and transcriptomic approaches to enhance Bifidobacterium animalis subsp. animalis growth and survival in milk

Project description:Bifidobacterium animalis subsp. animalis CNCM I-4602 was tested for its ability to grow in reconstituted skimmed milk (RSM). Strain CNCM I-4602 grows and survives poorly in reconstituted skimmed milk (RSM), although this was partially countered by the addition of certain compounds, including yeast extract, uric acid, glutathione, cysteine, ferrous sulfate and a combination of magnesium sulfate and manganese sulfate. Microarray analysis of the strain grown in RSM revealed a number of up-regulated amino acid biosynthetic pathways, as well as stress-related genes. Expression profiling by array

2021-03-03 | GSE112626 | GEO

Regulation mechanism of POX08340 and POX01907 in Penicillium oxalicum HP7-1 at the transcriptional level

Project description:In order to studing molecular mechanism of Raw Starch Digesting Glucoamylase production in Penicillium oxalicum ,we deleted POX01907 and POX08340 and analyzed the co-expression network of POX08340 and POX01907 at transcriptional level.

2024-07-08 | GSE245046 | GEO

Regulation mechanism of POX08340 and POX01907 in Penicillium oxalicum HP7-1 at the transcriptional level

2024-07-08 | GSE248520 | GEO

Modulation of gene expression induced by supercritical fluid rosemary extract in colon cancer cells

Project description:Supercritical rosemary extract (containing 16.90% carnosic acid, 1.90% carnosol and 13.59% volatile compounds) showed antitumor activity on colon cancer cells in vitro. We treated colon cancer cells with the extract and we employed whole genome microarray expression profiling to identify genes potentially involved in its antitumor mechanism of action. We analyzed gene expression of colon cancer SW620 cells after treating during 48h with supercritical rosemary extract at concentrations that cause 50% inhibition of cell viability (30 M-NM-<g/mL), citostatic effect (60 M-NM-<g/mL) and 50% cell death (100 M-NM-<g/mL), in comparison to control cells (0 M-NM-<g/mL). Two independent experiments were performed in triplicate. Each sample is the pool of the triplicates of one of the experiments (a or b) at the indicated concentration.

2014-04-04 | E-GEOD-56496 | biostudies-arrayexpress

Humulus lupulus brewing cultivars classification based on HPLC-MS metabolomic profiling

Project description:Dataset related to the article about metabolome based classification of Humulus lupulus brewing cultivars. There are two types of files: whole set of LC-HRMS profiling from IT-TOF, and .raw data from orbitrap with fragmentation of marker compounds (found in corresponding article) and major compounds of hops.

2022-06-28 | MSV000089747 | MassIVE

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data