Metabolomics

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GNPS - Metabolomic analysis of exosome of pancreatic cancer


ABSTRACT: Metabolomics analysis of serum exosomes isolated from pancreatic cancer patients and healthy controls.

INSTRUMENT(S): TripleTOF 4600 (AB SCIEX instrument model)

ORGANISM(S): Human

SUBMITTER: Juntuo Zhou  

PROVIDER: MSV000083669 | GNPS | Sat Apr 06 22:15:00 BST 2019

REPOSITORIES: GNPS

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Publications

Metabolomics identifies serum and exosomes metabolite markers of pancreatic cancer.

Tao Lianyuan L   Zhou Juntuo J   Yuan Chunhui C   Zhang Lingfu L   Li Deyu D   Si Dandan D   Xiu Dianrong D   Zhong Lijun L  

Metabolomics : Official journal of the Metabolomic Society 20190530 6


<h4>Introduction</h4>Pancreatic cancer (PC) is one of the most aggressive malignancies, and it's difficult to diagnosis PC at an early stage, which leads to the poor prognosis of PC.<h4>Objectives</h4>To identifiy the possible prognosis or dignosis metabolite biomarkers in the serum exosome of PC patients.<h4>Methods</h4>We employed LC-DDA-MS based untargeted lipidomic analysis to search for potential candidate biomarkers in the serum exosome of PC patients. Then LC-MRM-MS based targeted lipid q  ...[more]

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