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GNPS - Microbispora corallina and Nonomuraea

ABSTRACT: LC-MSMS analyses of extract coltures of Microbispora corallina producing the lantibiotic NAI-107 (aka microbisporicin) and Nonomuraea sp. ATCC39727 producing the glycopeptide A40926

OTHER RELATED OMICS DATASETS IN: PRJNA313047PRJNA201009

INSTRUMENT(S): LCQ Fleet

ORGANISM(S): Nonomuraea Sp Atcc39727 Microbispora Corallina

SUBMITTER: Marianna Iorio

PROVIDER: MSV000085123 | GNPS | Fri Mar 20 07:40:00 GMT 2020

REPOSITORIES: GNPS

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Characterization of the congeners in the lantibiotic NAI-107 complex.

Maffioli Sonia I SI Iorio Marianna M Sosio Margherita M Monciardini Paolo P Gaspari Eleonora E Donadio Stefano S

Journal of natural products 20140114 1

NAI-107, a lantibiotic produced by Microbispora sp. 107891, shows potent activity against multi-drug-resistant bacterial pathogens. It is produced as a complex of related molecules, which is unusual for ribosomally synthesized peptides. Here we describe the identification, characterization, and antibacterial activity of the congeners produced by Microbispora sp. 107891 and by the related Microbispora corallina NRRL 30420. These molecules differ by the presence of two, one, or zero hydroxyl group ...[more]

PMID: 24422756

Publication: 1/4

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