Metabolomics

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GNPS Comparable plasma lipid changes in patients with high-grade cervical intraepithelial neoplasia and patients with cervical cancer

ABSTRACT: Comparable plasma lipid changes in patients with high-grade cervical intraepithelial neoplasia and patients with cervical cancer

INSTRUMENT(S): ACQUITY UPLC H-Class, TripleTOF 5600

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Geum-Sook Hwang  

PROVIDER: MSV000086351 | GNPS | Thu Oct 22 00:02:00 BST 2020

REPOSITORIES: GNPS

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Comparable Plasma Lipid Changes in Patients with High-Grade Cervical Intraepithelial Neoplasia and Patients with Cervical Cancer.

Nam Miso M   Seo Sang-Soo SS   Jung Sunhee S   Jang Seo Young SY   Lee Jueun J   Kwon Minji M   Khan Imran I   Ryu Do Hyun DH   Kim Mi Kyung MK   Hwang Geum-Sook GS  

Journal of proteome research 20201126 1

Cervical cancer is the fourth most prevalent cancer among women worldwide and usually develops from cervical intraepithelial neoplasia (CIN). In the present study, we compared alterations in lipids associated with high-grade CIN and cervical cancer with those associated with a normal status and low-grade CIN by performing global lipid profiling on plasma (66 healthy controls and 55 patients with CIN1, 44 with CIN2/3, and 60 with cervical cancer) using ultraperformance liquid chromatography/quadr  ...[more]

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