Metabolomics

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GNPS Global LC-MS/MS based metabolomic profiling of Triphala


ABSTRACT: Triphala is a herbal formulation widely used in Ayurveda as a rejuvenation and revitalization therapy. Its constitutes include a mixture of dried extracts from Phyllanthus emblica, Terminalia chebula, and Terminalia bellirica. In this study, we employed an LC-MS/MS based strategy for global profiling of the constituent metabolites in Triphala.

INSTRUMENT(S): Sciex QTRAP 6500

ORGANISM(S): Terminalia Chebula (ncbitaxon:155022) Terminalia Bellirica (ncbitaxon:155021) Phyllanthus Emblica (ncbitaxon:296036)

SUBMITTER: T. S. Keshava Prasad  

PROVIDER: MSV000086784 | GNPS | Sun Jan 31 23:19:00 GMT 2021

REPOSITORIES: GNPS

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Publications

MS2Compound: A User-Friendly Compound Identification Tool for LC-MS/MS-Based Metabolomics Data.

Behera Santosh Kumar SK   Kasaragod Sandeep S   Karthikkeyan Gayathree G   Narayana Kotimoole Chinmaya C   Raju Rajesh R   Prasad Thottethodi Subrahmanya Keshava TSK   Subbannayya Yashwanth Y  

Omics : a journal of integrative biology 20210601 6


Metabolomics is a leading frontier of systems science and biomedical innovation. However, metabolite identification in mass spectrometry (MS)-based global metabolomics investigations remains a formidable challenge. Moreover, lack of comprehensive spectral databases hinders accurate identification of compounds in global MS-based metabolomics. Creating experiment-derived metabolite spectral libraries tailored to each experiment is labor-intensive. Therefore, predicted spectral libraries could serv  ...[more]

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