Ontology highlight
ABSTRACT:
INSTRUMENT(S): 6550 Quadrupole Time-of-Flight
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER: Nicola Zamboni
PROVIDER: MSV000087155 | GNPS | Sun Apr 04 13:38:00 BST 2021
REPOSITORIES: GNPS
Molecular systems biology 20221101 11
Cancer cells reprogram their metabolism to support growth and invasion. While previous work has highlighted how single altered reactions and pathways can drive tumorigenesis, it remains unclear how individual changes propagate at the network level and eventually determine global metabolic activity. To characterize the metabolic lifestyle of cancer cells across pathways and genotypes, we profiled the intracellular metabolome of 180 pan-cancer cell lines grown in identical conditions. For each cel ...[more]