Dataset Information

GNPS - C. elegans as a model for inter-individual variation in metabolism

ABSTRACT: Fox BW, Ponomarova O, Lee YU, Zhang G, Giese EG, Walker M, Roberto NM, Na H, Reis-Rodrigues P, Curtis BJ, Kolodziej AR, Crombie TA, Zdraljevic S, Yilmaz LS, Andersen EC, Schroeder FC, Walhout AJM (2022) C. elegans as a model for inter-individual variation in metabolism

INSTRUMENT(S): Q Exactive HF, Q Exactive

ORGANISM(S): Caenorhabditis Elegans (ncbitaxon:6239)

SUBMITTER: Frank Schroeder

PROVIDER: MSV000087810 | GNPS | Tue Jul 13 11:43:00 BST 2021

REPOSITORIES: GNPS

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C. elegans as a model for inter-individual variation in metabolism.

Fox Bennett W BW Ponomarova Olga O Lee Yong-Uk YU Zhang Gaotian G Giese Gabrielle E GE Walker Melissa M Roberto Nicole M NM Na Huimin H Rodrigues Pedro R PR Curtis Brian J BJ Kolodziej Aiden R AR Crombie Timothy A TA Zdraljevic Stefan S Yilmaz L Safak LS Andersen Erik C EC Schroeder Frank C FC Walhout Albertha J M AJM

Nature 20220706 7919

Individuals can exhibit differences in metabolism that are caused by the interplay of genetic background, nutritional input, microbiota and other environmental factors<sup>1-4</sup>. It is difficult to connect differences in metabolism to genomic variation and derive underlying molecular mechanisms in humans, owing to differences in diet and lifestyle, among others. Here we use the nematode Caenorhabditis elegans as a model to study inter-individual variation in metabolism. By comparing three wi ...[more]

PMID: 35794472

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