GNPS Penicillium_echinulatum_CONTIG4_RICE_15_g_SW_CD_200_g_20210824_FILTER

ABSTRACT: As part of our investigations on the chemical diversity of organisms from unexplored marine habitats of Mexico, a series of 29 fungal strains isolated from deep-sea sediments (more than 600 m deep) from the Gulf of Mexico were investigated. The antimicrobial potential of their organic extracts from solid cultures grown under the OSMAC approach was assessed against a panel of ESKAPE bacteria and the yeast C. albicans. Chemical studies on the active scaled-up cultures and some small-scale cultures led to the isolation of benzochromenones from Alternaria sp. CIGOM4, benzodiazepines from P. echinulatum CONTIG4, a cytochalsin from Biatriospora sp. CIGOM2, and an imidazopyridoindole from Penicillium sp. CIGOM10. Molecular network analysis by GNPS combined with manual dereplication showed the enormous potential of these fungi to produce bioactive compounds.

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Penicillium Echinulatum Cigom10

SUBMITTER: Rodrigo Villanueva-Silva  

PROVIDER: MSV000088216 | GNPS | Mon Oct 11 13:57:00 BST 2021

REPOSITORIES: GNPS