Metabolomics

Dataset Information

0

GNPS Burkholderia thailandensis-exposed Murine Airway Epithelial and Murine Macrophage Cells and Monocultures

ABSTRACT: Extraction samples of murine airways epithelial LA-4 cells and murine macrophage RAW264.7 cells cultures exposed to different amounts of B. thailandensis for varying periods of time. Extracts of the adherent cells and their respective conditioned media were analyzed with LC-MS/MS to identify compounds detected within the aforementioned samples. Included are extracts of B. thailandensis monocultures, B. thailandensis-exposed LA-4 and RAW264.7 mammalian cells, and LA-4 and RAW264.7 unexposed monocultures.

INSTRUMENT(S): impact II

ORGANISM(S): Burkholderia Thailandensis E264 (ncbitaxon:271848) Murine Airway Epithelial La-4 Murine Macrophage Raw264.7

SUBMITTER: Neha Garg  

PROVIDER: MSV000088693 | GNPS | Mon Jan 17 13:46:00 GMT 2022

REPOSITORIES: GNPS

Json Xml

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1
altmetric image

Publications

Metabolomics Analysis of Bacterial Pathogen <i>Burkholderia thailandensis</i> and Mammalian Host Cells in Co-culture.

Aiosa Nicole N   Sinha Anupama A   Jaiyesimi Olakunle A OA   da Silva Ricardo R RR   Branda Steven S SS   Garg Neha N  

ACS infectious diseases 20220629 8

The Tier 1 HHS/USDA Select Agent <i>Burkholderia pseudomallei</i> is a bacterial pathogen that is highly virulent when introduced into the respiratory tract and intrinsically resistant to many antibiotics. Transcriptomic- and proteomic-based methodologies have been used to investigate mechanisms of virulence employed by <i>B. pseudomallei</i> and <i>Burkholderia thailandensis</i>, a convenient surrogate; however, analysis of the pathogen and host metabolomes during infection is lacking. Changes  ...[more]

Similar Datasets

Genomics H3K4me1 ChIP-seq in murine pro-B cells
2016-10-25 | E-GEOD-79054 | biostudies-arrayexpress
Proteomics Precision N-glycoproteomics of murine peritoneal macrophage
2021-06-12 | PXD026629 | Pride
Transcriptomics Mouse Macrophage Cells: Control vs. Burkholderia pseudomallei infected cells
2011-07-15 | GSE30642 | GEO
Proteomics Mass spectrometry-based proteomic exploration of diverse murine macrophage cellular models
2024-10-28 | PXD051067 | Pride
Transcriptomics Mouse Macrophage Cells: Control vs. Burkholderia pseudomallei infected cells
2011-07-14 | E-GEOD-30642 | biostudies-arrayexpress
Transcriptomics Burkholderia pseudomallei transcriptional adaptation in macrophage
2011-12-31 | GSE27558 | GEO
Genomics Murine Pulmonary Interstitial Macrophage Subsets after Lipopolysaccharide
| PRJNA906080 | ENA
no omics defined Transcription profiling of Paracoccidioides brasiliensis yeast cells grown inside murine macrophages and in vitro
2006-09-22 | E-MEXP-823 | biostudies-arrayexpress
Transcriptomics Identification of two subsets of murine Kupffer cells
2021-09-01 | GSE168989 | GEO
Genomics Murine lung: Control vs Diesel Exhaust Exposed
| PRJNA941937 | ENA