Dataset Information

GNPS - Hadamard transform-Size Exclusion Chromatography-Charge Detection-Mass Spectrometry

ABSTRACT: Data on multiplex HT-SEC with online CD-MS detection. Data is included for beta galactosidase alone, in a mixture with GroEL, and for a high mass enriched E. coli lysate mixture

INSTRUMENT(S): Q Exactive UHMR

ORGANISM(S): Escherichia Coli (ncbitaxon:562)

SUBMITTER: Michael Marty

PROVIDER: MSV000095091 | GNPS | Thu Jun 20 08:56:00 BST 2024

REPOSITORIES: GNPS

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UniChromCD for Demultiplexing Time-Resolved Charge Detection-Mass Spectrometry Data.

Sanders James D JD Owen October N ON Tran Brian H BH Juetten Kyle J KJ Marty Michael T MT

Analytical chemistry 20240903 37

Charge detection mass spectrometry (CD-MS) enables characterization of large, heterogeneous analytes through the analysis of individual ion signals. Because hundreds to thousands of scans must be acquired to produce adequate ion statistics, CD-MS generally requires long analysis times. The slow acquisition speed of CD-MS complicates efforts to couple it with time-dispersive techniques, such as chromatography and ion mobility, because it is not always possible to acquire enough scans from a singl ...[more]

PMID: 39225436

Publication: 1/2

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