Metabolomics

Dataset Information

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GNPS - Fourier transform-Ion Mobility-Charge Detection-Mass Spectrometry


ABSTRACT: Fourier transform-ion mobility separations interfaced with charge detection-mass spectrometry detection. Contains data for GroEL, ADH, and GDH, the latter with varying step size, repeats, and drift voltages.

INSTRUMENT(S): Q Exactive UHMR

ORGANISM(S): No Species

SUBMITTER: Jennifer Brodbelt   Michael Marty  

PROVIDER: MSV000095092 | GNPS | Thu Jun 20 10:33:00 BST 2024

REPOSITORIES: GNPS

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Publications

UniChromCD for Demultiplexing Time-Resolved Charge Detection-Mass Spectrometry Data.

Sanders James D JD   Owen October N ON   Tran Brian H BH   Juetten Kyle J KJ   Marty Michael T MT  

Analytical chemistry 20240903 37


Charge detection mass spectrometry (CD-MS) enables characterization of large, heterogeneous analytes through the analysis of individual ion signals. Because hundreds to thousands of scans must be acquired to produce adequate ion statistics, CD-MS generally requires long analysis times. The slow acquisition speed of CD-MS complicates efforts to couple it with time-dispersive techniques, such as chromatography and ion mobility, because it is not always possible to acquire enough scans from a singl  ...[more]

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