Proteomic investigations of transcription factors critical in geniposide-mediated suppression of alcoholic steatosis and in overdose induced hepatotoxicity on liver
Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus Rattus
SUBMITTER: 
Jun Qin
PROVIDER: PXD014996 | iProX | Mon Aug 12 00:00:00 BST 2019
REPOSITORIES: iProX
Publications
Proteomic Investigations of Transcription Factors Critical in Geniposide-Mediated Suppression of Alcoholic Steatosis and in Overdose-Induced Hepatotoxicity on Liver in Rats.
Wei Junying J Man Qiong Q Ding Chen C Hu Yanzhen Y Liu Mingwei M Li Hui H Guo Feifei F Zhang Yi Y Li Defeng D Song Lei L Yang Hongjun H Tang Shihuan S
Journal of proteome research 20191022 11
Alcoholic steatosis is one of the most prevalent forms of liver disease, and appropriate insight and application of anti-steatosis drugs must be considered. Geniposide, the major active constituent of the <i>Gardenia jasminoides</i> (Ellis) fruit, has been commonly used as a traditional herbal medicine for the treatment of liver diseases. However, its hepatoprotective effect on alcoholic steatosis has not been reported. Moreover, geniposide overdose-induced hepatotoxicity was demonstrated. Hence ...[more]
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