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The proteomics analysis of ETV2-overexpressing dental pulp stem cells

ABSTRACT: DPSCs derivedgenerated from the three different donors were transfectedinfected with ETV2-overexpressing lentiviralrus particles or control lentiviralus particles. Protein samples were harvested after 10 days of endothelial differentiation. Proteome profiling was performed by the iProteome platform of the Fudan University Human Phenome Institute according to user guide.

ORGANISM(S): Homo Sapiens

SUBMITTER: Jianguang Xu

PROVIDER: PXD018138 | iProX | Sat Mar 21 00:00:00 GMT 2020

REPOSITORIES: iProX

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Upregulation of ETV2 Expression Promotes Endothelial Differentiation of Human Dental Pulp Stem Cells.

Li Jing J Zhu Youming Y Li Na N Wu Tao T Zheng Xianyu X Heng Boon Chin BC Zou Duohong D Xu Jianguang J

Cell transplantation 20210101

The lack of vasculogenesis often hampers the survivability and integration of newly engineered tissue grafts within the host. Autologous endothelial cells (ECs) are an ideal cell source for neovascularization, but they are limited by their scarcity, lack of proliferative capacity, and donor site morbidity upon isolation. The objective of this study was to determine whether differentiation of human dental pulp stem cells (DPSCs) into the endothelial lineage can be enhanced by recombinant ETV2 ove ...[more]

PMID: 33522307

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