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Proteome Analysis of the Extra-intestinal Pathogenic Escherichia coli (ExPEC) Extracellular Vesicles (EVs)

ABSTRACT: Label-free quantitative proteomic analysis of Extra-intestinal Pathogenic Escherichia coli (ExPEC) Extracellular Vesicles (EVs)

ORGANISM(S): Escherichia Coli

SUBMITTER: Xiangkai Zhuge

PROVIDER: PXD020207 | iProX | Wed Oct 12 00:00:00 BST 2022

REPOSITORIES: iProX

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Reductions in bacterial viability stimulate the production of Extra-intestinal Pathogenic Escherichia coli (ExPEC) cytoplasm-carrying Extracellular Vesicles (EVs).

Jiang Min M Wang Zhongxing Z Xia Fufang F Wen Zhe Z Chen Rui R Zhu Dongyu D Wang Min M Zhuge Xiangkai X Dai Jianjun J

PLoS pathogens 20221019 10

Extra-intestinal Pathogenic Escherichia coli (ExPEC) is defined as an extra-intestinal foodborne pathogen, and several dominant sequence types (STs) ExPEC isolates are highly virulent, with zoonotic potential. Bacteria extracellular vesicles (EVs) carry specific subsets of molecular cargo, which affect various biological processes in bacteria and host. The mechanisms of EVs formation in ExPEC remains to be elucidated. Here, the purified EVs of ExPEC strains of different STs were isolated with ul ...[more]

PMID: 36260637

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