Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus Rattus
SUBMITTER: Qiang Liu
PROVIDER: PXD027219 | iProX | Mon Jul 12 00:00:00 BST 2021
REPOSITORIES: iProX
Zhu Zhaoming Z Chen Tingting T Wang Zhuxian Z Xue Yaqi Y Wu Wenfeng W Wang Yuan Y Du Qunqun Q Wu Yufan Y Zeng Quanfu Q Jiang Cuiping C Shen Chunyan C Liu Li L Zhu Hongxia H Liu Qiang Q
Frontiers in pharmacology 20210901
The label-free methods of proteomic combined with metabolomics were applied to explore the mechanisms of Cryptotanshinone (CPT) intervention in rats with acne. The model group consisted of rats given oleic acid (MC), then treated with CPT, while control groups did not receive treatment. The skin samples were significantly different between control, model and CPT-treated groups in hierarchical clustering dendrogram. Obvious separations of the skin metabolic profiles from the three groups were fou ...[more]