Proteomics

Dataset Information

0

Biological characteristics of cefiderocol-resistant Klebsiella pneumoniae and the mechanism of reduced biofilm-forming ability—From the perspective of proteome and transcriptome

ABSTRACT: In the present study, we collected cefiderocol 16 resistant K. pneumoniae isolates during a 36-day acclimatization procedure while increasing the 17 cefiderocol concentration in the culture medium. Strains were studied for changes in their 18 biological characteristics using proteomics and transcriptomics

ORGANISM(S): Klebsiella Pneumoniae Subsp. Pneumoniae Ntuh-k2044

SUBMITTER: Chenbing Wang  

PROVIDER: PXD028717 | iProX | Thu Sep 23 00:00:00 BST 2021

REPOSITORIES: iProX

Json Xml
altmetric image

Publications

Proteomic and Transcriptomic Analyses Indicate Reduced Biofilm-Forming Abilities in Cefiderocol-Resistant <i>Klebsiella pneumoniae</i>.

Bao Jinfeng J   Xie Lu L   Ma Yating Y   An Ran R   Gu Bing B   Wang Chengbin C  

Frontiers in microbiology 20220103

The advent of cefiderocol provides hope for the clinical treatment of multi-drug resistant gram-negative bacteria (GNB), especially those with carbapenem resistance. Resistance of <i>Klebsiella pneumoniae</i> to cefiderocol can be enhanced by acclimatization. In the present study, we collected cefiderocol resistant <i>K. pneumoniae</i> isolates during a 36-day acclimatization procedure while increasing the cefiderocol concentration in the culture medium. Strains were studied for changes in their  ...[more]

Similar Datasets

Proteomics Synergistic effects of polymyxin and vancomycin combinations on carbapenem- and polymyxin-resistant Klebsiella pneumoniae and their molecular characteristics
2023-10-13 | PXD045685 | JPOST Repository
Other Characterization of plasmids mediating carbapenem resistance in Klebsiella pneumoniae in Pretoria, South Africa
2019-10-17 | GSE138949 | GEO
Transcriptomics Genomic and Transcriptional Characterisation of Carbapenem and Colistin Resistance Mechanisms in Klebsiella pneumoniae
2022-11-07 | GSE217148 | GEO
Transcriptomics Gene expression in Klebsiella pneumoniae
2017-12-25 | GSE24688 | GEO
Transcriptomics Klebsiella pneumoniae: WT vs. Hfq mutant
2013-01-11 | GSE29448 | GEO
Transcriptomics Bdellovibrio RNA seqence (Klebsiella pneumoniae)
2021-04-09 | GSE112863 | GEO
Transcriptomics Host Immune Response to Clinical Hypervirulent Klebsiella pneumoniae Pulmonary Infections via Transcriptome Analysis
2021-03-30 | GSE171048 | GEO
Proteomics Shotgun Proteomic Analysis of ESBL and non ESBL Producing Klebsiella Pneumoniae Clinical Isolates
2022-02-24 | PXD011558 | Pride
Proteomics Shotgun Proteomic Analysis of ESBL and non ESBL Producing Klebsiella Pneumoniae Clinical Isolates
2021-04-16 | PXD011693 | Pride
Proteomics klebsiella pneumoniae serum exposure
2023-10-16 | MSV000093124 | MassIVE