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Effects of cinnamic acid and cinnamic aldehyde on db/db mice

ABSTRACT: db/db mice were treated with cinnamic acid and cinnamic aldehyde for 4 weeks and the liver samples were used for proteome analysis.

ORGANISM(S): Mus Musculus

SUBMITTER: Tonghua Liu

PROVIDER: PXD029385 | iProX | Thu Oct 28 00:00:00 BST 2021

REPOSITORIES: iProX

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Mechanisms for Improving Hepatic Glucolipid Metabolism by Cinnamic Acid and Cinnamic Aldehyde: An Insight Provided by Multi-Omics.

Wu You Y Wang Ming-Hui MH Yang Tao T Qin Tian-Yu TY Qin Ling-Ling LL Hu Yao-Mu YM Zhang Cheng-Fei CF Sun Bo-Ju BJ Ding Lei L Wu Li-Li LL Liu Tong-Hua TH

Frontiers in nutrition 20220111

Cinnamic acid (AC) and cinnamic aldehyde (AL) are two chemicals enriched in cinnamon and have been previously proved to improve glucolipid metabolism, thus ameliorating metabolic disorders. In this study, we employed transcriptomes and proteomes on AC and AL treated db/db mice in order to explore the underlying mechanisms for their effects. Db/db mice were divided into three groups: the control group, AC group and AL group. Gender- and age-matched <i>wt</i>/<i>wt</i> mice were used as a normal g ...[more]

PMID: 35087857

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