Proteomics

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Aortic dissection molecular markers using iTRAQ combined with Label Free techniques


ABSTRACT: To screen serum molecular markers systematically amid aortic dissection and acute coronary syndrome, preliminary identify the pathogenesis of acute aortic dissection.

ORGANISM(S): Homo Sapiens

SUBMITTER: Jianyun Yan  

PROVIDER: PXD032857 | iProX | Fri Mar 25 00:00:00 GMT 2022

REPOSITORIES: iProX

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Study on Proteomics-Based Aortic Dissection Molecular Markers Using iTRAQ Combined With Label Free Techniques.

Deng Ting T   Liu Yongguang Y   Gael Akindavyi A   Fu Xiaohua X   Deng Xiaofang X   Liu Yunfeng Y   Wu Yizhang Y   Wu Yingzhi Y   Wang Huimin H   Deng Yuying Y   Lai Jun J   Fu Qiang Q  

Frontiers in physiology 20220715


<b>Background:</b> Aortic dissection refers to the separation of aortic media and extension along the long axis to form the true and false chambers of the aortic wall. 65-70% of the patients died of cardiac tamponade, arrhythmia, dissection rupture, etc. At present, echocardiography, computed tomography angiography (CTA), etc. are the main diagnosis tools for aortic dissection. To date, there is no rapid serum molecular marker that can be used for differential diagnosis and risk assessment. <b>O  ...[more]

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