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Salmonella enterica Serovar Typhimurium transcriptional regulator STM0347 mediates Flagellar Phase Variation via Hin invertase

ABSTRACT: To elucidate the STM0347 regulon in S. Typhimurium, we performed a quantitative proteomic profiling of stm0347 deletion mutant, compared with its parental WT strain.

ORGANISM(S): Salmonella Enterica Subsp. Enterica Serovar Typhimurium Str. Sl1344

SUBMITTER: Qinghua Zou

PROVIDER: PXD034943 | iProX | Mon Jun 27 00:00:00 BST 2022

REPOSITORIES: iProX

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Salmonella Regulator STM0347 Mediates Flagellar Phase Variation via Hin Invertase.

Wang Hongou H Tang Zhiheng Z Xue Baoshuai B Lu Qinghui Q Liu Xiaoyun X Zou Qinghua Q

International journal of molecular sciences 20220730 15

Salmonella enterica is one of the most important food-borne pathogens, whose motility and virulence are highly related to flagella. Flagella alternatively express two kinds of surface antigen flagellin, FliC and FljB, in a phenomenon known as flagellar phase variation. The molecular mechanisms by which the switching orientation of the Hin-composed DNA segment mediates the expression of the fljBA promoter have been thoroughly illustrated. However, the precise regulators that control ...[more]

PMID: 35955615

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