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Electroacupuncture Activated Local Sympathetic Noradrenergic Signaling to relieve synovitis and referred pain behaviors in KOA Rats

ABSTRACT: Electroacupuncture Activated Local Sympathetic Noradrenergic Signaling to relieve synovitis and referred pain behaviors in KOA Rats

ORGANISM(S): Rattus Norvegicus

SUBMITTER: Wei He

PROVIDER: PXD038461 | iProX | Tue Nov 29 00:00:00 GMT 2022

REPOSITORIES: iProX

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Electroacupuncture activated local sympathetic noradrenergic signaling to relieve synovitis and referred pain behaviors in knee osteoarthritis rats.

Chen Wei W Zhang Xiao-Ning XN Su Yang-Shuai YS Wang Xiao-Yu XY Li Heng-Cong HC Liu Yi-Han YH Wan Hong-Ye HY Qu Zheng-Yang ZY Jing Xiang-Hong XH He Wei W

Frontiers in molecular neuroscience 20230307

<h4>Introduction</h4>Recent research has focused on the local control of articular inflammation through neuronal stimulation to avoid the systemic side effects of conventional pharmacological therapies. Electroacupuncture (EA) has been proven to be useful for inflammation suppressing and pain reduction in knee osteoarthritis (KOA) patients, yet its mechanism remains unclear.<h4>Methods</h4>In the present study, the KOA model was established using the intra-articular injection of sodium monoiodoa ...[more]

PMID: 36959872

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