Dataset Information
Circulating proteome profiling of Guangzhou Nutrition and Health Study
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Jusheng Zheng
PROVIDER: PXD039231 | iProX | Tue Jan 03 00:00:00 GMT 2023
REPOSITORIES: iProX
Publications
Genome-wide genotype-serum proteome mapping provides insights into the cross-ancestry differences in cardiometabolic disease susceptibility.
Nature communications 20230216 1
Identification of protein quantitative trait loci (pQTL) helps understand the underlying mechanisms of diseases and discover promising targets for pharmacological intervention. For most important class of drug targets, genetic evidence needs to be generalizable to diverse populations. Given that the majority of the previous studies were conducted in European ancestry populations, little is known about the protein-associated genetic variants in East Asians. Based on data-independent acquisition m ...[more]
