Proteomics

Dataset Information

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AD-MCI-CN proteomic data (LFQ, DDA)


ABSTRACT: This data included proteomic data of 57 Alzheimer's disease patients, 43 mild cognitive patients and 62 cognitively normal controls.

ORGANISM(S): Homo Sapiens

SUBMITTER: Dantao Peng  

PROVIDER: PXD044672 | iProX | Fri Aug 18 00:00:00 BST 2023

REPOSITORIES: iProX

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Publications

Identification of novel diagnostic panel for mild cognitive impairment and Alzheimer's disease: findings based on urine proteomics and machine learning.

Wang Yuye Y   Sun Yu Y   Wang Yu Y   Jia Shuhong S   Qiao Yanan Y   Zhou Zhi Z   Shao Wen W   Zhang Xiangfei X   Guo Jing J   Zhang Bin B   Niu Xiaoqian X   Wang Yi Y   Peng Dantao D  

Alzheimer's research & therapy 20231104 1


<h4>Background</h4>Alzheimer's disease is a prevalent disease with a heavy global burden. Proteomics is the systematic study of proteins and peptides to provide comprehensive descriptions. Aiming to obtain a more accurate and convenient clinical diagnosis, researchers are working for better biomarkers. Urine is more convenient which could reflect the change of disease at an earlier stage. Thus, we conducted a cross-sectional study to investigate novel diagnostic panels.<h4>Methods</h4>We firstly  ...[more]

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