Proteomics

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MCPIP2 competes with IGF2BP1 binding to common stem-loop structure in the 3’UTRs of pro-angiogenic genes for suppressing breast tumor angiogenesis-2


ABSTRACT: This study was performed according to RNA pull-down assay using biotin-labeled WT RNA probe (with stem-loop structure) or mutant RNA probe (without stem-loop structure) and streptavidin-coated Dynabeads in human breast tumor cell MDA-MB-468, and then the pulled down proteins were isolated by SDS-PAGE and silver staining, and identified by high resolution mass spectrometry.

ORGANISM(S): Homo Sapiens

SUBMITTER: Wenbao Lu  

PROVIDER: PXD052920 | iProX | Wed Jun 05 00:00:00 BST 2024

REPOSITORIES: iProX

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