Proteomics

Dataset Information

0

Identification of HLA class I immunopeptide from human colon tissue (Tumor)

ABSTRACT: HLA Class I immunopeptides were affinity purified by W6/32 antibody and analyzed by Orbitrap Fusion Lumos with FAIMS. Personalized database which includes patient-specific somatic mutations obtained from whole exome sequencing (WES) data was used for database search. Identification results were filtered at 1% FDR thresholds by searching against a randomized decoy database using Proteome Discoverer 2.4 (Sequest HT).

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Koji UEDA 

PROVIDER: PXD023805 | JPOST Repository | Sat Aug 20 00:00:00 BST 2022

REPOSITORIES: jPOST

Json Xml

Dataset's files

Source:
Action DRS
200727_Lumos_FAIMS_CID_IT_CVSet1_1ul_51T.raw Raw
200727_Lumos_FAIMS_CID_IT_CVSet1_1ul_60T.raw Raw
200727_Lumos_FAIMS_CID_IT_CVSet1_1ul_78T.raw Raw
200727_Lumos_FAIMS_CID_IT_CVSet1_1ul_84T.raw Raw
200727_Lumos_FAIMS_CID_IT_CVSet1_5ul_51T.raw Raw
Items per page:
1 - 5 of 20
altmetric image

Publications

Differential ion mobility mass spectrometry in immunopeptidomics identifies neoantigens carrying colorectal cancer driver mutations.

Minegishi Yuriko Y   Kiyotani Kazuma K   Nemoto Kensaku K   Inoue Yoshikage Y   Haga Yoshimi Y   Fujii Risa R   Saichi Naomi N   Nagayama Satoshi S   Ueda Koji K  

Communications biology 20220818 1

Understanding the properties of human leukocyte antigen (HLA) peptides (immunopeptides) is essential for precision cancer medicine, while the direct identification of immunopeptides from small biopsies of clinical tissues by mass spectrometry (MS) is still confronted with technical challenges. Here, to overcome these hindrances, high-field asymmetric waveform ion mobility spectrometry (FAIMS) is introduced to conduct differential ion mobility (DIM)-MS by seamless gas-phase fractionation optimal  ...[more]

Similar Datasets

Proteomics Identification of HLA class I immunopeptide from human colon tissue (Normal)
2022-08-20 | PXD023804 | JPOST Repository
Proteomics Comparison of efficacy in immunfopeptide identification from HCT116 by "with" FAIMS
2022-08-20 | PXD023771 | JPOST Repository
Proteomics Global identification of HCT116 immunopeptides by FAIMS-assisted immunopeptidomics
2022-08-20 | PXD023773 | JPOST Repository
Proteomics Comparison of efficacy in immunopeptide identification from HCT116 by "without" FAIMS
2022-08-20 | PXD023770 | JPOST Repository
Proteomics HepG2 HLA-I immunopeptidome by immunoprecipitation
2023-09-07 | PXD045203 |
Unknown Combined analysis of HLA class I, HLA-E and HLA-G predicts prognosis in colon cancer patients.
| S-EPMC3899753 | biostudies-other
Proteomics HLA class I ligandome of HCT15/b2m
2022-11-15 | PXD024248 | JPOST Repository
Transcriptomics Transcription profiling of nouse TNBS-induced murine colitis
2008-06-14 | E-GEOD-5864 | biostudies-arrayexpress
Proteomics Systematic HLA Epitope Ranking Pan Algorithm (SHERPA)
2021-06-15 | PXD023064 | Pride
Transcriptomics Deep sequencing of gastric carcinoma reveals somatic mutations relevant to personalized medicine
2012-10-25 | E-GEOD-29999 | biostudies-arrayexpress