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Preservation of collagen in the soft tissue of frozen mammoths

ABSTRACT: To evaluate whether collagen is preserved in the soft tissues of frozen mammoths for 40,000 years, we performed protein identification of mammoth lung and kidney (and elephant bone and kidney as controls) after trypsin digestion.

ORGANISM(S): Mammuthus Primigenius Elephas Maximus Indicus

SUBMITTER: Shunji Hattori

PROVIDER: PXD024006 | JPOST Repository | Tue Oct 05 00:00:00 BST 2021

REPOSITORIES: jPOST

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			Action	DRS
	Elephant%20bone.wiff	Wiff
	Elephant%20bone.wiff.scan	Wiff
	Elephant%20bone_1.mzML	Mzml
	Elephant%20bone_2.mzML	Mzml
	Elephant%20bone_3.mzML	Mzml

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Preservation of collagen in the soft tissues of frozen mammoths.

Hattori Shunji S Kiriyama-Tanaka Tomomi T Kusubata Masashi M Taga Yuki Y Ebihara Testuya T Kumazawa Yuki Y Imai Katsuyuki K Miura Mitsutaka M Mezaki Yoshihiro Y Tikhonov Alexei A Senoo Haruki H

PloS one 20211029 10

We investigated the characteristics of extracellular matrix (ECM) in the soft tissue of two frozen baby woolly mammoths (Mammuthus primigenius) that died and were buried in Siberian permafrost approximately 40,000 years ago. Morphological and biochemical analyses of mammoth lung and liver demonstrated that those soft tissues were preserved at the gross anatomical and histological levels. The ultrastructure of ECM components, namely a fibrillar structure with a collagen-characteristic pattern of ...[more]

PMID: 34714842

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