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Necrotizing enterocolitis rat_DFAT cell treatment_ileum

ABSTRACT: Quantification of proteins in the ileum of Necrotizing enterocolitis.

ORGANISM(S): Rattus Rattus (black Rat)

SUBMITTER: Atsuto Onoda

PROVIDER: PXD025647 | JPOST Repository | Wed Apr 27 00:00:00 BST 2022

REPOSITORIES: jPOST

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			Action	DRS
	NEC_DFAT_Raw.txt	Txt
	NEC_DFAT_Raw.xlsx	Xlsx

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Publications

Dedifferentiated fat cells administration ameliorates abnormal expressions of fatty acids metabolism-related protein expressions and intestinal tissue damage in experimental necrotizing enterocolitis.

Mimatsu Haruka H Onoda Atsuto A Kazama Tomohiko T Nishijima Koji K Shimoyama Yoshie Y Go Shoji S Ueda Kazuto K Takahashi Yoshiyuki Y Matsumoto Taro T Hayakawa Masahiro M Sato Yoshiaki Y

Scientific reports 20230522 1

Neonatal necrotizing enterocolitis (NEC) is a serious disease of premature infants that necessitates intensive care and frequently results in life-threatening complications and high mortality. Dedifferentiated fat cells (DFATs) are mesenchymal stem cell-like cells derived from mature adipocytes. DFATs were intraperitoneally administrated to a rat NEC model, and the treatment effect and its mechanism were evaluated. The NEC model was created using rat pups hand fed with artificial milk, exposed t ...[more]

PMID: 37217485

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