Ontology highlight
ABSTRACT:
ORGANISM(S): Orientia Tsutsugamushi
SUBMITTER: Jeanne Salje
PROVIDER: PXD028218 | JPOST Repository | Wed May 11 00:00:00 BST 2022
REPOSITORIES: jPOST
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Nature communications 20220623 1
Orientia tsutsugamushi (Ot) is an obligate intracellular bacterium in the family Rickettsiaceae that causes scrub typhus, a severe mite-borne human disease. Its mechanism of cell exit is unusual amongst Rickettsiaceae, as Ot buds off the surface of infected cells enveloped in plasma membrane. Here, we show that Ot bacteria that have budded out of host cells are in a distinct developmental stage compared with intracellular bacteria. We refer to these two stages as intracellular and extracellular ...[more]