Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Masaaki Oyama
PROVIDER: PXD030039 | JPOST Repository | Thu Apr 20 00:00:00 BST 2023
REPOSITORIES: jPOST
Items per page: 5 1 - 5 of 20 |
Fujikawa Daichi D Nakamura Takanori T Yoshioka Daisuke D Li Zizheng Z Moriizumi Hisashi H Taguchi Mari M Tokai-Nishizumi Noriko N Kozuka-Hata Hiroko H Oyama Masaaki M Takekawa Mutsuhiro M
Current biology : CB 20230428 10
Cytoplasmic stress granules (SGs) are phase-separated membrane-less organelles that form in response to various stress stimuli. SGs are mainly composed of non-canonical stalled 48S preinitiation complexes. In addition, many other proteins also accumulate into SGs, but the list is still incomplete. SG assembly suppresses apoptosis and promotes cell survival under stress. Furthermore, hyperformation of SGs is frequently observed in various human cancers and accelerates tumor development and progre ...[more]