SJIA serum proteome profiling with DIA-MS
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Hironori Sato, Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba
PROVIDER: PXD030413 | JPOST Repository | Tue Apr 26 00:00:00 BST 2022
REPOSITORIES: jPOST
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| sJIAserum_MAS1.raw | Raw | |||
| sJIAserum_MAS2.raw | Raw | |||
| sJIAserum_MAS3.raw | Raw | |||
| sJIAserum_MAS4.raw | Raw | |||
| sJIAserum_MAS5.raw | Raw |
Items per page: 5 1 - 5 of 20 |
Publications
In-Depth Serum Proteomics by DIA-MS with <i>In Silico</i> Spectral Libraries Reveals Dynamics during the Active Phase of Systemic Juvenile Idiopathic Arthritis.
Sato Hironori H Inoue Yuzaburo Y Kawashima Yusuke Y Nakajima Daisuke D Ishikawa Masaki M Konno Ryo R Nakamura Ren R Kato Daigo D Mitsunaga Kanako K Yamamoto Takeshi T Yamaide Akiko A Tomiita Minako M Hoshioka Akira A Ohara Osamu O Shimojo Naoki N
ACS omega 20220215 8
In serum proteomics using mass spectrometry, the number of detectable proteins is reduced due to high-abundance proteins, such as albumin. However, recently developed data-independent acquisition mass spectrometry (DIA-MS) proteomics technology has made it possible to remarkably improve the number of proteins in a serum analysis by removing high-abundance proteins. Using this technology, we analyzed sera from patients with systemic juvenile idiopathic arthritis (sJIA), a rare pediatric disease. ...[more]
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