Proteomics

Dataset Information

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Mouse periodontal ligament tissue after orthodontic tooth movement


ABSTRACT: Mouse periodontal ligament tissue after orthodontic tooth movement for 14 days. Tissue was dissected by a laser microdissection microscope. Samples were analyzed separately at mesial (compression) and distal (tension) sides.

ORGANISM(S): Mus Musculus (mouse)

SUBMITTER: Masaru Kaku 

PROVIDER: PXD030430 | JPOST Repository | Fri Dec 16 00:00:00 GMT 2022

REPOSITORIES: jPOST

Dataset's files

Source:
Action DRS
Control_Distal-1.mgf Mgf
Control_Distal-2.mgf Mgf
Control_Distal-3.mgf Mgf
Control_Mesial-1.mgf Mgf
Control_Mesial-2.mgf Mgf
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Publications

Extracellular Matrix-Oriented Proteomic Analysis of Periodontal Ligament Under Mechanical Stress.

Thant Lay L   Kaku Masaru M   Kakihara Yoshito Y   Mizukoshi Masaru M   Kitami Megumi M   Arai Moe M   Kitami Kohei K   Kobayashi Daiki D   Yoshida Yutaka Y   Maeda Takeyasu T   Saito Isao I   Uoshima Katsumi K   Saeki Makio M  

Frontiers in physiology 20220520


The periodontal ligament (PDL) is a specialized connective tissue that provides structural support to the tooth and is crucial for oral functions. The mechanical properties of the PDL are mainly derived from the tissue-specific composition and structural characteristics of the extracellular matrix (ECM). The ECM also plays key roles in determining cell fate in the cellular microenvironment thus crucial in the PDL tissue homeostasis. In the present study, we determined the comprehensive ECM profi  ...[more]

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